Innate Immune Cells

Innate Immune Cells

To the tune of “One and Only” by Adele

[Verse 1]
The macrophage
Of the innate immune system
Kills and eliminates
Invading pathogens
Bound material
It is internalized
In phagolysosomes
Microbes meet their demise

[Pre-Chorus]
Macrophages will remove
Apoptotic cells
And aged and damaged cells
With great efficiency
Based on function and their phenotype
There are both killer and healer kinds

[Chorus]
The innate immune cells
And molecules
Have the ability to
Recognize pathogens
This can help to initiate
The induced innate
Immune response
And inflammation

[Verse 2]
The neutrophil
The most abundant leukocyte
They are the first cells
At the infection site
They are short-lived
And cannot multiply
And they engulf
The microbes which they bind

[Pre-Chorus]
Eosinophils
Primarily release
Their contents
To the environment
This kills fungi and parasites
And protozoa
Those too large for phagocytes

[Chorus]
The innate immune cells
And molecules
Have the ability to
Recognize pathogens
This can help to initiate
The induced innate
Immune response
And inflammation

[Bridge] x6
The first defence
Against invading cells

[Chorus]
The innate immune cells
And molecules
Have the ability to
Recognize pathogens
This can help to initiate
The induced innate
Immune response
And inflammation
This can help to initiate
The induced innate
Immune response
And inflammation