Regulation of Heart Rate

Regulation of Heart Rate

To the tune of “Drift Away” from Steven Universe

[Verse 1]
Action potentials
By the pacemaker
Affect the heart rate
The autonomic
Nervous system
It will innervate 

[Pre-Chorus]
The sympathetic
Nervous system
It releases
Norepinephrine

[Chorus]
Which binds to Beta
Adrenergic
Receptors to increase the heart rate

[Verse 2]
Vagal tone from the
PSNS
Predominates at rest
 Reducing heart rate
Of the pacemaker
Below endogenous

[Pre-Chorus]
The PSNS
It releases
The neurotransmitter
Acetylcholine

[Chorus]
Which binds to M2
Muscarinic
Receptors to decrease the heart rate

[Bridge]
Autonomic nervous system
Alters the heart rate
Alters the heart rate
By changing leak permeabilities
It does not affect the shape or
The duration of
The duration of
The duration of
Action potentials

[Verse 3]
These cell receptors
Bind neurotransmitters
And are G-protein linked
Changing the likelihood
Of ion
Channels for opening

[Pre-Chorus]
This will alter
The spontaneous
Pacemaker potential
That these cells exhibit

[Chorus]
The autonomic
Nervous system
It will change
The heart
The heart
The heart rate